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Amino acid separation by preparative temperature-swing chromatography with flow reversal

Identifieur interne : 002363 ( Main/Exploration ); précédent : 002362; suivant : 002364

Amino acid separation by preparative temperature-swing chromatography with flow reversal

Auteurs : Gabor Simon [France, Hongrie] ; Laszlo Hanak [Hongrie] ; Georges Grévillot [France] ; Tibor Szanya [Hongrie] ; Gyula Marton [Hongrie]

Source :

RBID : ISTEX:196888CAFC80226BC5635E6A3D90A331662655AC

English descriptors

Abstract

Abstract: A special type of adsorptive parametric pumping called temperature-swing chromatography is experimentally investigated for a new application: the separation of amino acids. Experiments have been done with a mixture of arginine, histidine and lysine in acidic solution (HCl). A multicomponent equilibrium model has been used to simulate the experimental results and to investigate some possible ways to improve the separation. It is shown that it is possible to separate these amino acids, and the composition of the products strongly depends on the experimental conditions. Arginine with purity greater than 95% can be obtained by applying these methods.

Url:
DOI: 10.1016/0021-9673(95)01184-6


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">Abstract: A special type of adsorptive parametric pumping called temperature-swing chromatography is experimentally investigated for a new application: the separation of amino acids. Experiments have been done with a mixture of arginine, histidine and lysine in acidic solution (HCl). A multicomponent equilibrium model has been used to simulate the experimental results and to investigate some possible ways to improve the separation. It is shown that it is possible to separate these amino acids, and the composition of the products strongly depends on the experimental conditions. Arginine with purity greater than 95% can be obtained by applying these methods.</div>
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